Guidance on regulations for the transport of infectious substances 2025-2026: applicable as from 1 October 2025

Overview

Ensuring the safe transport of infectious substances is essential to protect public health and prevent accidental exposure during increasingly complex global movements of biological materials. This document provides updated technical guidance aligned with international regulations applicable from 1 October 2025, supporting stakeholders involved in the shipment of infectious substances across all modes of transport.

It outlines the regulatory frameworks governing transport at international, regional and national levels, promoting harmonization with United Nations model regulations and modal agreements. The guidance clarifies the roles and responsibilities of key actors and provides detailed procedures for defining, classifying and packaging infectious substances, including the application of triple packaging systems and relevant packing instructions. It also addresses marking, labelling and documentation requirements, as well as training, risk management, incident response, and regulatory considerations related to customs, permits and security. Intended for public health institutions, laboratories, logistics providers and regulatory authorities, this publication supports compliance and safe practices in the transport of infectious substances.